It is possible to develop a tolerance to CBD, just like many other drugs and chemicals. If you find that it is not working as well after some time, try taking a few days off to reset your system before starting again on a low dose. The answer to whether patients can develop a tolerance to medical cannabis is both yes and no. This is because the tolerance profiles are different for THC and CBD, the two main active components of medical cannabis.
While frequent use of medical cannabis leads to greater tolerance to THC, the same is not necessarily true for CBD. Tolerance should not be confused with physical addiction or dependence. People who drink coffee frequently will find that they must drink more to feel the same effects as when they first started drinking. This is because the body develops a tolerance to substances in order to protect itself from potential harm.
THC or tetrahydrocannabinol is the psychoactive ingredient responsible for making users feel “high”, while CBD or cannabidiol is considered to be the medicinal element that has been shown to alleviate the symptoms of anxiety, chronic pain, depression and nerve pain. Unlike THC, CBD does not cause any intoxicating effects. However, THC demonstrates clear health benefits for patients suffering from pain, lack of appetite, insomnia and PTSD. The good news is that CBD does not seem to create a tolerance in regular users.
This is because CBD and THC do not bind to CB1 receptors in the same way. As a result, when CBD binds to these receptors, they are not desensitized. Understanding these mechanisms is crucial for safe and effective cannabis use. People who use CBD regularly may find that they need more of it in order to experience the same effects as when they first started using it.
This natural tolerance has less to do with the consumption of CBD and more to do with the body's ability to absorb it. Over time, you may accumulate enough endocannabinoids to be able to use less CBD or not even need it. If you have tolerance problems or are suffering from withdrawal, seek advice from your doctor on how to give CBD a chance to help you on the road to recovery. Some people may feel that they need more CBD than others to experience the same effects, even if they haven't consumed cannabidiol for a long enough period of time to develop a tolerance.
In fact, it's not just about CBD: tolerance can occur with any type of medication or supplement, whether they're over-the-counter or prescription drugs.By understanding how CBD tolerance works, you can ensure that you're using the cannabinoid as effectively as possible. If you regularly use marijuana, you may be wondering if your tolerance to THC will affect your tolerance to CBD. That's why, for medical cannabis patients who rely primarily on things like CBD oil or CBD-dominant cannabis strains, CBD tolerance isn't something to worry about. If you use CBD for medical purposes and have developed a tolerance to it, talk to your doctor about other treatment options. An excess of THC can cause high tolerance, while, on the contrary, if you develop a tolerance to CBD, you may become more sensitive to it; this effect occurs over a long period of regular daily use.